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产品目录

重组小鼠IFN-gamma R1(CD119)(C端含His标签)图片
产品货号:
JN1411
中文名称:
重组小鼠IFN-gamma R1(CD119)(C端含His标签)
英文名称:
Recombinant Mouse Interferon gamma Receptor 1
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala26-Asp253在C端含有His标签。

IFN-gamma R1/CD119质量控制:>95%(还原性SDS-PAGE)

IFN-gamma R1/CD119制剂:冻干品

IFN-gamma R1/CD119保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

IFN-gamma R1/CD119复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于IFN-gamma R1/CD119
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).
相关搜索:重组小鼠IFN-gamma R1(CD119)(C端含His标签)Recombinant Mouse Interferon gamma Receptor 1
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